ACUTE TOXICITY OF ADENOSINE 3', 5'-CYCLIC MONOPHOSPHATE
نویسندگان
چکیده
منابع مشابه
Renal Effects of Adenosine 3 ' , 5 ' - Cyclic Monophosphate and Dibutyryl Adenosine 3 , 5 ' - Cyclic Monophosphate
An abstract of this work appeared in 1970 Abstracts, The American Society of Nephrology. Received for publication 27 October 1970 and in revised form 28 January 1971. similar to the effect of renal arterial infusion of isoproterenol. The results suggest that synthesis of cyclic AMP in proximal renal tubule cells in response to stimulation of beta adrenergic or other receptors can mediate a decr...
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The urinary excretion of cyclic adenosine 3',5'-monophosphate (cAMP), corrected for urinary creatinine, was determined in 177 patients with primary or metastatic tumours and in 149 normal subjects. In 26 patients with malignancy and in 10 control subjects the excretion of cyclic guanosine 3',5'-monophosphate (cGMP) was also evaluated. The urinary cAMP/Cr ratio in human neoplasms of epithelial o...
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Binding of cyclic adenosine 3' ,5'-monophosphate (cAMP) by the cAMP receptor protein in crude cell-free extracts of Escherichia coli was characterized. When cell were grown in glucose, binding was inhibited 50% relative to extracts from cells grown with succinate as carbon source . This inhibition could be relieved by dialysis.
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The adenine nucleotides, 5'-AMP and 3',5'-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5'-AMP, and rates of uridine transport are increased after incubation with either 5'-AMP or cyclic AMP. On the contrary, cyclic AMP levels are increased and uridine transport decreased in cells treated with an inhibi...
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The cAMP-signaling pathway is composed of multiple components ranging from receptors, G proteins, and adenylyl cyclase to protein kinase A. A common view of the molecular interaction between them is that these molecules are disseminated on the plasma lipid membrane and random collide with each other to transmit signals. A limitation to this idea, however, is that a signaling cascade involving m...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 1976
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.1.2_15